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抗小鼠CD11b抗體, 克隆號(hào)M1/70, APC



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品    牌:STEMCELL TECHNOLOGIES

貨    號(hào):60001AZ

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DeepBio得分:
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抗小鼠CD11b抗體, 克隆號(hào)M1/70, APC
交貨周期:7
100μg 獨(dú)家代理
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北京礪達(dá)辰生物科技有限公司
庫(kù)存:99

  • 產(chǎn)品詳情

The M1/70 antibody reacts with CD11b, an ~170 kDa type 1 transmembrane glycoprotein which associates non-covalently with CD18 to form the heterodimeric Mac-1 receptor. Through its interactions with ligands such as ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen, Mac-1 functions in several processes, including the adherence of neutrophils and monocytes to stimulated endothelium and phagocytosis of complement-coated particles. CD11b is expressed on the surface of granulocytes, monocytes, NK cells, dendritic cells, tissue macrophages, and subsets of T and B cells, and has been used as a marker to distinguish na?ve and memory CD8+ T cells. CD11b is a relatively late marker for myeloid differentiation and is undetectable on most myelomonocytic hematopoietic progenitor cells and more primitive cells. The M1/70 antibody reportedly blocks iC3b binding to Mac-1. This antibody clone has been verified for purity assessments of cells isolated with EasySep? kits, including EasySep? Mouse Monocyte Isolation Kit (Catalog #19861).

友情鏈接 :  中國(guó)科學(xué)院 國(guó)科控股 喀斯瑪控股有限公司 中科海外人才創(chuàng)業(yè)園

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